The Empire portrayed in Asimov's novels is in turmoil – he cited Gibbon's Decline and Fall of the Roman Empire as an influence. Beset by overconsumption, corruption and inefficiency, "it had been falling for centuries before one man really became aware of that fall. That man was Hari Seldon, the man who represented the one spark of creative effort left among the gathering decay. He developed and brought to its highest pitch the science of psycho-history."
Seldon is a scientist and prophet who predicts the Empire's fall. He sets up his Foundation in a remote corner of the galaxy, hoping to build a new civilisation from the ruins of the old. The Empire attacks the Foundation with all its military arsenal and tries to crush it. Seldon uses a religion (based on scientific illusionism) to further his aims. These are tracked by the novel and its sequels across a vast tract of time. For the most part, his predictions come true.
Seldon, like Bin Laden, transmits videotaped messages for his followers, recorded in advance. There is also some similarity in geopolitical strategy. Seldon's vision seems oddly like the way Bin Laden has conceived his campaign. "Psycho-history" is the statistical treatment of the actions of large populations across epochal periods – the science of mobs as Asimov calls it. "Hari Seldon plotted the social and economic trends of the time, sighted along curves and foresaw the continuing and accelerating fall of civilisation."